产品货号：
Z20743
中文名称：
MPO抗体
英文名称：
Anti-MPO Antibody
产品规格：
2mL
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MPO Antibody |
| 指标别名 | MPO;myeloperoxidase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | MPO |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Myeloperoxidase [Human Leukocytes] |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was prepared from monospecific antiserum by a delipidation and defibrination.Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-rabbit serum,purified and partially purified Myeloperoxidase [Human Leukocytes].Cross-reactivity against Myeloperoxidase from other tissues and species may occur but have not been specifically determined. |
| 浓度 | 75mg/mL by Refractometry |
| 产品形态 | Lyophilized |
| 保存条件 | Store vial at 4℃ prior to restoration.For extended storage aliquot contents and freeze at -20℃ or below.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.?Expiration date is one (1) year from date of opening. |
| 背景资料 | Human myeloperoxidase (MPO) is a dimeric protein composed of two heavy subunits (53kDa) and two light subunits (15kDa).Each MPO molecule contains two prosthetic porphyrins which play an important role in the catalytic cycle.Molecular weights for MPO isoforms from pools of normal human samples range from 114,000 to 140,000 daltons reflecting a heterogeneous mixture of isoforms when assayed under non-reducing conditions of SDS-PAGE.Often MPO from a single donor will yield a homogenous preparation reflecting a single isoform.The carbohydrate component of MPO,consisting of mannose,glucose and N-acetylglucosamine residues is 2.5%.MPO is inhibited by azide and other compounds.MPO is stored in primary granules of neutrophils and serves as a bactericidal agent in that MPO catalyzes the production of hypochlorous acid (HOCl),a powerful oxidant.HOCl is derived from chloride ion (Cl-) and hydrogen peroxide (H2O2).In a number of inflammatory situations,MPO is released into the extracellular matrix where its measurement can be used as an indication of neutrophil activation. |
| Uniprot ID | P05164 |
| 推荐稀释比 | ELISA:1:200,000 IP:1:100 WB:1:5,000 |
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